Northumbria Police received a report that an altercation had taken place in Times Square, outsides the Centre for Life, sometime between 3am and 3.15am on Tuesday, April 25.
Officers have said that CCTV footage taken from the area shows a man had suffered significant facial injuries.
One man has been arrested and released on bail, pending further police inquiries.
Police are now keen to trace the victim of the incident, who they say was wearing a black jumper and blue jeans at the time.
Officers are asking the individual, or anyone who knows them, to get in touch via the ‘Tell us Something’ page of the Northumbria Police website or call 101, quoting crime number 051455R/23.
Read Newcastle’s news on the go with our free email newsletters - bringing the headlines to your inbox. Catch up on the day’s news and sport and enjoy even more from the NewcastleWorld team. Visit our website here to find out more and sign up.