The likes of Nick Pope, Kieran Trippier, Sven Botman, Bruno Guimaraes, Elliot Anderson, Allan Saint-Maximin and Callum Wilson started against The Eagles and played out a 2-2 draw in the first half.
The in-form Miguel Almiron was twice on the scoresheet before Eddie Howe changed his entire line-up at half-time, bringing on the likes of Dan Burn, Fabian Schar, Matty Bondswell, Jonjo Shelvey, Joe Willock and Chris Wood.
A red card for Joelinton and a hamstring injury Jonjo Shelvey disrupted Newcastle in the latter stages with Benfica finding a late winner to lift the Eusebio Cup.
NewcastleWorld takes a look at the 10 players that missed United’s 3-2 defeat at the Estadio da Luz.