All eyes will be on the Denmark international, who is likely to be included in Thomas Frank’s matchday plans for the first time since joining in January.
The 30-year-old hasn’t played a competitive match since suffering a cardiac arrest during his country’s Euro 2020 opening group game with Finland in June.
Despite recovering, Eriksen was forced to leave Inter Milan after being told he was unable to play in Italy due to having an implanted cardioverter defibrillator (ICD) fitted.
Christan Eriksen steps up emotional return
As a result, The Bees snapped up the former Tottenham Hotspur midfielder on a free transfer, and he has since played in two behind closed doors friendlies.
Last Monday, he assisted one of Josh Da Silva’s three goals in a 3-2 win against Southend United.
Yesterday, Eriksen doubled that assists tally as goals from Mathias Jorgensen and Tristan Crama earned a 2-2 draw with Rangers XI.
Having impressed in both training fixtures, Eriksen is expected to make a remarkable return to senior football against the Magpies.
Speaking about Eriksen’s situation last week, Frank said: “He feels well, and is in a good place.
“He’s been out for seven months, and normally you need a proper pre-season to get it going. But he came to us with a good foundation, so he doesn’t need six weeks.
“We have another good opponent for a friendly game on Monday, then we are aiming for the Newcastle game.”
Mathias Jorgensen and Ivan Toney could also return
Saturday could also see the return of top scorer Ivan Toney.
The former Magpies striker, who netted in the 3-3 draw between the two sides at St James’ Park earlier in the season, has sat out of the last three games.
The 25-year-old wasn’t far off returning against Arsenal last weekend, meaning his inclusion versus Newcastle is more than likely.
Elsewhere, Jorgensen, who scored and played alongside Eriksen on Monday, is set to come back into contention.
The central defender has missed the previous 15 league matches with a thigh injury - last playing in early-November.
Eddie Howe’s men will leapfrog Brentford in the Premier League table should they leave the capital with three points.
Frank’s side, now will relegation fears of their own, are winless in their last eight matches in all competitions, whereas Newcastle have picked up 10 points from a possible 12 in their last four matches.