Newcastle United's European adventure is over following the 2-1 defeat to AC Milan on Wednesday night. Disappointment still lingers but there's little time for a Champions League hangover.
In-form Fulham are the visitors to St James' Park in the Premier League this afternoon as the Magpies look to avoid a fourth successive defeat in all competition.
United suffered back-to-back losses to Everton and Tottenham Hotspur on their travels last week but a return to home turf, where they have only once in the league this season, is welcomed.
Howe's squad has been decimated by injuries in recent months but the return of Callum Wilson, Sean Longstaff and Dan Burn has come as a major boost.
However, Newcastle still remain without several first-team players. Fulham, who have won back-to-back matches by 5-0, also have a few of their stars out.
Here, NewcastleWorld takes a look at the players ruled out of today's fixture on Tyneside, and those that are a doubt:
9. Matt Targett - out
Targett was substituted very early on against Manchester United after suffering a hamstring injury. The left-back has undergone surgery on the injury and will thus miss the next few months of action. | AFP via Getty Images
10. Joe Willock - doubt
Willock reaggravated an achilles injury and has missed every game since the international break. He too won't return until January. | Getty Images
11. Elliot Anderson - out
Anderson has been ruled out with a back injury and whilst he is expected to miss the busy festive period, a return not too long after the new year could be on the cards. | Getty Images
12. Kieran Trippier - out
Trippier picked up his fifth Premier League booking of the season last weekend and will serve a one-game suspension on Saturday. He also suffered a minor injury in midweek. | AFP via Getty Images