Newcastle United are in Champions League action against AC Milan this evening (kick-off 8pm) - but will it be for the final time this season?
The Group F permutations are simple. Win, and Paris Saint-Germain drop points away to Borussia Dortmund, then a place into the last 16 of the competition is secured.
But regardless of PSG's result, avoiding defeat against the Italian giants at St James' Park will at least guarantee a place in the Europa League. Lose, and United drop out of Europe for the second-half of the campaign altogether.
Milan too have everything to play for. If they win and PSG lose in Germany, then it will be Stefano Pioli's side who clinch second spot in the group.
The circumstances set up a huge occasion on Tyneside for both two teams who have had their fair share of injury problems in the build-up to the fixture.
Here, NewcastleWorld takes you through the latest injury news from both camps, with 22 players expected to miss out, plus four doubts:
1. Nick Pope - out
The Magpies' No.1 underwent surgery on a dislocated shoulder last week and won't return until April.
2. Sven Botman - out
The Dutchman hasn't featured since the 8-0 win at Sheffield United in September because of a knee issue.
3. Matt Targett - out
Targett underwent hamstring surgery last month and isn't expected to return until February.
4. Elliot Anderson - out
Anderson also has a back injury but a return at the end of December to early January is on the cards.