Newcastle United are in Champions League action against AC Milan this evening (kick-off 8pm) - but will it be for the final time this season?
The Group F permutations are simple. Win, and Paris Saint-Germain drop points away to Borussia Dortmund, then a place into the last 16 of the competition is secured.
But regardless of PSG's result, avoiding defeat against the Italian giants at St James' Park will at least guarantee a place in the Europa League. Lose, and United drop out of Europe for the second-half of the campaign altogether.
Milan too have everything to play for. If they win and PSG lose in Germany, then it will be Stefano Pioli's side who clinch second spot in the group.
The circumstances set up a huge occasion on Tyneside for both two teams who have had their fair share of injury problems in the build-up to the fixture.
Here, NewcastleWorld takes you through the latest injury news from both camps, with 22 players expected to miss out, plus four doubts:
13. Alex Murphy - out
Ineligible to play under UEFA 'B List' rules having only joined Newcastle in 2022. Must have trained with the club for three years. | Getty Images for Premier League
14. Martin Dubravka - doubt
Suffering with illness. A late check will be made on his fitness. | AFP via Getty Images
15. Sean Longstaff - doubt
Wasn't spotted in training on Tuesday and Howe gave little away when asked about the midfielder. | Getty Images
16. Anthony Gordon - doubt
Wasn't spotted in training on Tuesday and Howe gave little away when asked about the winger. | AFP via Getty Images