Newcastle United are in Champions League action against AC Milan this evening (kick-off 8pm) - but will it be for the final time this season?
The Group F permutations are simple. Win, and Paris Saint-Germain drop points away to Borussia Dortmund, then a place into the last 16 of the competition is secured.
But regardless of PSG's result, avoiding defeat against the Italian giants at St James' Park will at least guarantee a place in the Europa League. Lose, and United drop out of Europe for the second-half of the campaign altogether.
Milan too have everything to play for. If they win and PSG lose in Germany, then it will be Stefano Pioli's side who clinch second spot in the group.
The circumstances set up a huge occasion on Tyneside for both two teams who have had their fair share of injury problems in the build-up to the fixture.
Here, NewcastleWorld takes you through the latest injury news from both camps, with 22 players expected to miss out, plus four doubts:
21. Mattia Caldara - out
Had an operation on his ankle in September. Expected to be out for a lengthy period. | Getty Images
22. Marco Sportiello - out
The goalkeeper came on in the closing stages against Newcastle at the San Siro. Currently out with a calf issue. | Getty Images
23. Marco Pellegrino - out
Pellegrino has appeared just once in Serie A this season. Left out of Champions League squad. | Getty Images
24. Ismael Bennacer - out
Bennacer was left out AC Milan's Champions League squad. | Getty Images