Yoane Wissa bagged a brace off the bench to get Matthias Jaissle off to a flying start as Newcastle United manager.
Filip Ugrinic fired Valencia into an early lead with a curling effort from outside the area. Moments later, Anthony Elanga wrongfully had a goal disallowed before his night was cruelly ended due to a Jose Gaya horror challenge.
The resulting red card allowed the Magpies to take control - with Jaissle proactively making four changes at the break. Wissa and Bazoumana Toure, in particular, proved to be inspired substitutions.
The Toon No.9 scored shortly after the restart and looked lively throughout before combining with Toure late on to seal the victory. Here are your NewcastleWorld player ratings.
5. Miodrag Pivas - 5
A natural centre-back, the youngster was shoehorned into the team at full-back. It would be harsh to criticise Pivas too severely but he did not look up to this level. | Getty Images
6. Aladji Bamba - 5
Did ok in his first Toon start. Was caught wanting positionally on occasion. Again, the 20-year-old is still finding his feet at senior level. Another who was hooked at half-time. | AFP via Getty Images
7. Jacob Ramsey - 6
The more composed of the two starting midfielders. That said, his wayward pass to Barnes led to the opener. Came close with a drilled shot but Newcastle need to see more from him. | Getty Images
8. Anthony Elanga - 7
An extremely cruel night for the Swede. Elanga was once again Newcastle’s brightest spark - and had a goal wrongfully disallowed - before being on the wrong end of a horror tackle from Jose Gaya. Word is that he will be ok. | Getty Images