Newcastle United’s line-up versus Wolves: Shock news and key duo miss out - plus Alexander Isak

Eddie Howe has been forced into two changes against Wolverhampton Wanderers - with Bruno Guimaraes a shock absence.

Sean Longstaff replaces the Brazilian in midfield, who is ruled out with a knock. Meanwhile, Chris Wood comes in for the injured Callum Wilson.

There’s no place for club record signing Alexander Isak in the matchday squad following his arrival on Friday.

The 22-year-old’s involvement at Molineux was subject to international clearance and a work permit, with the latter not yet received.

Speaking to Sky Sports ahead of the game, Howe said of Isak: He told Sky Sports: “(It’s) just a work permit issue.

“Right until the last minute we were waiting but it didn’t come.”

Howe also addressed Bruno’s absence and the selection of Chris Wood to replace the injured Wilson.

“He (Bruno) picked up a little niggle during the week,” he explained.

“That will be a loss to us today, but we have a couple of players coming in fresh, so we look forward to seeing them.

“Chris has never let us down since he’s joined the club, I think he’s been superb for us.

“He scored in midweek and played very well, so looking forward to seeing him perform well for the team.”

Martin Dubravka is missing for the second consecutive match amid interest from Manchester United.

On the game this afternoon, Howe said: “It’s very early to draw too many conclusions from anything really at this stage but Wolves are an outstanding team.

“They’ve signed very well, they’ve recruited very well - if you look at the quality of the players they have in midfield, they’ve got three or four very good technicians in there and some very good attacking players.

“We don’t underestimate them at all. Bruno’s done a great job and now I think they’re a bit more fluid - they play different systems. They’re a dangerous team.”

Newcastle United XI: NickPope, Kieran Trippier, Fabian Schar, Sven Botman, Dan Burn, Sean Longstaff, Joelinton, Joe Willock, Miguel Almiron, Chris Wood, Allan Saint-Maximin.

Subs: Karl Darlow, Paul Dummett, Jamaal Lascelles, Matt Ritchie, Matt Targett, Javier Manquillo, Ryan Fraser, Jacob Murphy, Elliot Anderson.