With three away games to come in seven days, Howe was expected to rotate his team selection to deal with the physical demand.
However, the 44-year-old has hinted at keeping changes to minimum as United look to extend their unbeaten run to nine matches when they visit St Mary’s
Asked if he will rotate his side, Howe said: “I think it’s difficult to give you clarity at this moment in time for obvious reasons but yes possibly we will look to try and right decisions for the team in the next game.
“In our position now, and the run that we’ve been on - I’ve said all through this run, I’m reluctant to change things dramatically because the team has lacked rhythm for a long time so when you get rhythm, you want to try and enhance that, not disrupt it.
“I’ve kept changes to a minimum and that doesn’t mean I don’t believe in the players I’m not using. I believe in them and I believe they can all play a huge role in the future.
“I’ve just got to deal with the here and now and that’s what I’ve tried to do.”
Supporters are keen to see more of £35million January signing Bruno Guimaraes.
The Brazilian midfielder has made five appearances since joining from Lyon - all of which have been cameos from the bench.
Howe added: “I never promise a player that I’ll play them in certain games ahead because you’re then planning for something you don’t know how the situation will be.
“When it comes to game day, I’m not going to say 100% we’ll make changes. I’ll have to assess it from what I’ve seen in the previous game and then try and make the right call.
“It is an opportunity I think for players who haven’t played to impress.”