Howe plans to ring the changes for the visit of Bilabo after beating Serie A side Atalanta 1-0 last night.
The likes of Nick Pope, Dan Burn, Matt Targett and Chris Wood - who scored the only goal of the game from the spot - won’t feature against Bilbao.
It was left to academy graduate Elliot Anderson to steal the show on Friday, which has strengthened his hopes of being part of Howe’s first team squad this season.
Minutes are key in pre-seasona nd Howe will have the opportunity to hand most players up to 90 minutes ahead of hosting Nottingham Forest next Saturday.
Here, NewcastleWorld takes a look at the starting XI Howe is expected to name against Bilbao:
9. RW: Matt Ritchie
Ritchie was brought on at right wing against Benfica and he’s expected to continue there versus Benfica. | Getty Images
10. LW: Allan Saint-Maximin
Looked devastating at times against Benfica but didn’t aways produce in the final third. | Getty Images
11. ST: Callum Wilson
Newcastle’s talisman - it’ll be surprise if Wilson doesn’t start against Notts Forest. Photo: Stu Forster
12. SUBS
Mark Gillespie, Matty Longstaff, Lucas De Bolle, Santiago Munoz, Matty Bondswell, Dylan Stephenson, Jay Turner-Cooke, Alex Murphy, Lewis Miley. | Getty Images